Phytomedicine in Neuroprotection: Exploring Plant-Derived Bioactive Compounds, Molecular Mechanisms, and Therapeutic Strategies Against Neurodegenerative Disorders
- Dr. Satya Narayan Naik Indian Institute of Technology Delhi, India guesteditor.phytomedicine@gmail.com
Call for Papers – Special Issue
Biological Sciences, published by IR Research Publication, invites original research articles, scholarly reviews, and short communications for the special issue "Phytomedicine in Neuroprotection: Exploring Plant-Derived Bioactive Compounds, Molecular Mechanisms, and Therapeutic Strategies Against Neurodegenerative Disorders."
Neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, and related neurological conditions, represent major challenges to global healthcare. These disorders involve complex pathological mechanisms, including oxidative stress, neuroinflammation, mitochondrial dysfunction, protein aggregation, and progressive neuronal loss.
Plant-derived bioactive compounds and natural products have attracted substantial scientific interest as potential sources of neuroprotective agents. Their diverse chemical structures and biological activities offer opportunities to investigate novel therapeutic targets and mechanisms of action.
This special issue aims to bring together high-quality research investigating phytomedicine-based strategies for neuroprotection, with particular emphasis on the identification, extraction, characterization, biological evaluation, and therapeutic potential of plant-derived compounds.
Contributions exploring molecular mechanisms, pharmacological activities, phytochemical characterization, neurodegenerative disease models, innovative delivery technologies, and translational applications are especially encouraged.
Guest Editor
Dr. Satya Narayan Naik
Indian Institute of Technology Delhi, India
The collection seeks to bridge natural product research, pharmaceutical sciences, molecular neuroscience, and translational medicine to advance evidence-based phytotherapeutic strategies for neurological disorders.
All submissions will undergo the journal's standard editorial screening and independent peer-review process.
Submitting to a Special Issue
Authors must prepare and submit their manuscripts through the online submission portal, select the appropriate special issue or conference proceedings collection under the “For the Editors” step, and clearly mention the collection title in their cover letter; for detailed submission requirements, please refer to the Author Guidelines.
No articles have been published in this issue yet. Accepted papers will appear here as a full table of contents, exactly like a regular issue.
About this Special Issue
Aims & scope
This special issue aims to advance scientific understanding of plant-derived bioactive compounds and their potential applications in neuroprotection and the management of neurodegenerative disorders.
The collection focuses on the identification, extraction, characterization, and biological evaluation of phytochemicals and natural products that may influence neuronal survival, neuroinflammation, oxidative stress, mitochondrial function, protein aggregation, and other molecular pathways associated with neurological disease.
Particular emphasis will be placed on mechanistic investigations addressing neuroprotective signalling pathways, antioxidant and anti-inflammatory responses, neuroimmune interactions, synaptic function, and cellular responses to neurodegenerative stress.
The scope includes experimental studies involving Alzheimer's disease, Parkinson's disease, Huntington's disease, and related neurological conditions, as well as the application of innovative extraction technologies, phytochemical standardization, advanced drug delivery systems, and computational approaches to natural product-based therapeutic development.
Studies assessing pharmacokinetics, bioavailability, blood–brain barrier penetration, toxicity, efficacy, and translational feasibility of plant-derived bioactive compounds are also encouraged.
The special issue welcomes original experimental investigations, preclinical research, comprehensive reviews, and short communications supported by rigorous scientific evidence.
The overarching objective is to connect traditional natural product knowledge with modern biomedical research to identify scientifically validated opportunities for neuroprotection and neurological therapeutics.
Topics of interest
- Phytomedicine and Neuroprotection
- Plant-Derived Bioactive Compounds
- Natural Products in Neurodegenerative Disorders
- Alzheimer's Disease and Phytotherapeutics
- Parkinson's Disease and Natural Product-Based Interventions
- Oxidative Stress and Neuronal Damage
- Neuroinflammation and Anti-Inflammatory Phytochemicals
- Mitochondrial Dysfunction and Neuroprotection
- Protein Aggregation and Neurodegenerative Mechanisms
- Molecular Mechanisms of Plant-Derived Neuroprotective Agents
- Phytochemical Extraction and Characterization
- Standardization and Quality Control of Herbal Extracts
- Natural Product Pharmacology and Toxicology
- Blood–Brain Barrier Permeability and Drug Delivery
- Nanotechnology-Based Delivery of Phytochemicals
- Bioavailability and Pharmacokinetics of Natural Compounds
- Neuroprotective Signalling Pathways
- Preclinical Models of Neurodegenerative Diseases
- Computational Screening of Natural Neuroprotective Compounds
- Translational Development of Phytotherapeutics
Manuscript types accepted
- Original Research Article
- Review Article
- Short Communication