Evaluation of Antibiotics Prescribing Patterns practiced at Panjab University Health Centre, Chandigarh

Anil Kumar; Beenta; Megha Chakraborty

doi:10.55006/biolsciences.2023.3302

Authors

Anil Kumar University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
Beenta University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
Megha Chakraborty University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India https://orcid.org/0009-0005-7411-6588

DOI:

https://doi.org/10.55006/biolsciences.2023.3302

Keywords:

Antibiotics, Prescription monitoring, Rationale prescribing patterns, Antimicrobial Resistance, URI, WHO Prescribing indicators

Abstract

Prescription Monitoring Program is a WHO initiative to encourage rationality in drug prescribing patterns among health practitioners based on observational cohort studies to assess, monitor, and regulate drug usage in primary healthcare centers. The objective of this study is to understand the present trends of Antibiotics prescribing followed by physicians at Panjab University Healthcare Centre in order to assess and evaluate the rationale use of Antibiotics. A cross-sectional observational study was conducted at PUHC Outpatient Department for 2 months from 1st October to 30th November 2022. A total of 100 prescriptions were studied. This study included a diverse group of population on a random basis. The data collection and assessment were in accordance with WHO Prescription Performa. During this period, 100 prescriptions were collected and analyzed from OPD patients based on WHO Performa. The Demographic study showed that out of 100 prescriptions, 44% were female and 56% male followed by 25% pediatric (1-20 years) and 4%, geriatric. The study of age demographics revealed most prescription was of 21-40 years (age-group). The most common indication for antibiotics prescribing was found to be Upper Respiratory Tract Infections (URI). The majority of patients visiting PUHC were diagnosed with URI (86 prescriptions out of 100) followed by ENT & eye infections, burn wound and bacterial typhoid fever. Out of total antibiotics prescriptions, 50.71% brand drugs and 49.29% generic drugs were prescribed. The most frequently prescribed antibiotic was among Macrolides class which was Azithromycin. The average cost of antibiotics per prescription was Rs. 68.57. Out of 100 patients 81% were aware about dosage regimen and 86% patients had knowledge about medication indication. Only 37% of patients were familiar with therapeutic category of drug. According to evaluation, 68% of prescriptions were in accordance with WHO Prescribing Indicators. The study reflected the current prescribing pattern of antibiotics in PUHC and highlights the drawbacks for scope of improvement in rationale prescribing of drugs.

Downloads

Download data is not yet available.

References

(1) Ahmad A, Megha R, Irfanul H and Pravina A: Study the prescription pattern of antibiotics in the medicine department in a teaching hospital. IJTPR 2014.

(2) Divya Kancherla et al., A Study On Prescribing Pattern of Antibiotics In Respiratory Tract Infections In A Tertiary Care Center. International Journal of Recent Scientific Research Vol. 6, Issue, 6, pp.4558-4563, June, 2015

(3) Kumar SG, Adithan C, Harish BN, Sujatha S, Roy G, Malini A. Antimicrobial resistance in India: A review. J Nat Sc Biol Med 2013;4:286-91.

(4) Kaye, K.; Pogue, J. Infections Caused by Resistant Gram-Negative Bacteria: Epidemiology and Management.Pharm. J. Hum. Pharmacol. Drug Ther. 2015, 35, 949–962

(5) Bisht R, Katiyar A, Singh R, Mittal P. Antibiotic resistance–A global issue of concern. Asian J. Pharm. Clin. Res. 2009; 2(2):34-39

(6) O'Neil J. Tackling drug-resistant infections globally: final report and recommendations. In: Ro A, ed. Resistance. London, United Kingdom: 2016; 1, 84.

(7) Brown, L., Langelier, C., Reid, M. J., Rutishauser, R. L., & Strnad, L. (2017). Antimicrobial Resistance: A Call to Action!. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 64(1), 106–107.

(8) Tula M, Iyoha O, Iruolaje F. Antibiotic resistance: challenges and prospect for therapy in developing countries. Br J Pharm Res. 2015;8(3):1–16.

(9) Kumar A, Jain P, Upadhyaya P, Jain S. A study monitoring prescription pattern of antibiotics in atertiary care hospital in North India. International Journal of Basic & ClinicalPharmacology2014;3(6):1006-113

(10) Sneddon J, Afriyie D, Sefah I, Cockburn A, Kerr F, Byrne-Davis L, Cameron E. Developing a Sustainable Antimicrobial Stewardship (AMS) Programme in Ghana: Replicating the Scottish Triad Model of Information, Education and Quality Improvement. Antibiotics (Basel). 2020 Sep 23;9(10):636.

(11) Jain S, Upadhyaya P, Goyal J, et al. A systematic review of prescription pattern monitoring studies and their effectiveness in promoting rational use of medicines. Perspect Clin Res. 2015;6(2):86-90.

(12) Tobi H, Faber A, vanden Berg PB, Drane JW, de Jong-van den Berg LT. Studying co-medication patterns: The impact of definitions. Pharmacoepidemiol Drug Saf 2007;16:405-11.

(13) Pathak A, Gupta VK, MauryaA, Kumar A, Singh A. Assessment of drug prescribing pattern using WHO indicators in hospitalized patients at a tertiary care teaching hospital in rural area of India. Int J Basic Clin Pharmacol 2016;5:651-5.

(14) Randad RD, Bhagwate ST, Inamdar MK. Drug utilization study of some antibiotic in indoor setting at tertiary care teaching hospital in Central India: a descriptive study. Int J Basic Clin Pharmacol 2017;6:1123-6.