Phytochemical and antibacterial activity of Khaya senegalinesis Leaves Extracts with different solvent

Najib Muhammad; R.S. Saidu; B. Abdullahi; C.C Odenigbo; Zayyanu Iyya

doi:10.55006/biolsciences.2024.4401

Authors

Najib Muhammad School of Science Laboratory Technology Chemistry, Federal Polytechnic, Kaura-Namoda, Nigeria https://orcid.org/0000-0001-6220-5552
R.S. Saidu School of Science Laboratory Technology Chemistry, Federal Polytechnic, Kaura-Namoda, Nigeria
B. Abdullahi School of Science Laboratory Technology Chemistry, Federal Polytechnic, Kaura-Namoda, Nigeria
C.C Odenigbo School of Science Laboratory Technology Chemistry, Federal Polytechnic, Kaura-Namoda, Nigeria
Zayyanu Iyya School of Science Laboratory Technology Chemistry, Federal Polytechnic, Kaura-Namoda, Nigeria

DOI:

https://doi.org/10.55006/biolsciences.2024.4401

Keywords:

Phytochemicals, Qualitative, Quantitative, Khaya senegalinesis, Test organism

Abstract

Phytochemical content as the main source of new antibiotics due to the presence of phytochemicals. The objectives of the research are to evaluate the phytochemical and antibacterial activity of Khaya senegalensis leaf extracts. Against different solvents and were subjected to phytochemical and antibacterial tests using Agar well diffusion method. Methanol extracts of all plant extracts Saponins are present only but absent in K. senegalensis from methanol extract. In addition, alkaloids are present in all crude methanol extracts. Steroids are found in K. Senegalinesis. Therefore, based on the pronounced activity of the extracts against the test bacteria, alkaloids, flavonoids and saponins were found to be 11.80 ± 0.02, followed by flavonoids from the extracts of acetate with a value of 10.33 ± 0.02, then they are also found in saponins. n-hexane extracts with a value of 9.6 ± 0.02, the minimum found in methanol respectively 1.77 ± 0.01. It can be suggested that this plant has potential as a source of therapeutic agents. Crude extracts showed different zones of inhibition against Staphylococcus aureus, Baccilus subtilis, with different concentrations, MIC was shown without turbidity. It is therefore suggested that more studies are carried out using different solvents and to isolate and identify the active ingredients present in the extracts to support these claims

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